Weight Regain Prevention

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Mechanisms of Weight Regain following Weight Loss

Obesity is a world-wide pandemic and its incidence is on the rise along with associated comorbidities. Currently, there are few effective therapies to combat obesity. The use of lifestyle modification therapy, namely, improvements in diet and exercise, is preferable over bariatric surgery or pharmacotherapy due to surgical risks and issues with drug efficacy and safety. Although they are initia...

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Depression as a Predictor of Weight Regain Among Successful Weight Losers in the Diabetes Prevention Program

OBJECTIVE To determine whether depression symptoms or antidepressant medication use predicts weight regain in overweight individuals with impaired glucose tolerance (IGT) who are successful with initial weight loss. RESEARCH DESIGN AND METHODS A total of 1,442 participants who successfully lost at least 3% of their baseline body weight after 12 months of participation in the randomized contro...

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An exercise outpost in weight regain territory.

MARKERS of cardiovascular and metabolic health are consistently improved with modest weight loss; yet, from a physiological perspective, weight loss is a very tough task to achieve (3). Changes during weight loss affect neural, endocrine, autocrine, and paracrine responses that orchestrate complex metabolic and physiological interactions predominantly favoring weight preservation (6). In fact, ...

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A peripheral perspective of weight regain.

BODY WEIGHT REGULATION is sensitive to a number of environmental, social, and genetic pressures but is ultimately subject to a homeostatic control system linked with adiposity (23, 36). This control system involves a closed-feedback loop between the central nervous system and the peripheral tissues, whereby the central nervous system interprets a complex set of signals from the periphery and su...

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The Economic Impact of Weight Regain

Background. Obesity is well known for being associated with significant economic repercussions. Bariatric surgery is the only evidence-based solution to this problem as well as a cost-effective method of addressing the concern. Numerous authors have calculated the cost effectiveness and cost savings of bariatric surgery; however, to date the economic impact of weight regain as a component of ov...

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ژورنال

عنوان ژورنال: Clinical Diabetes

سال: 2008

ISSN: 0891-8929,0891-8929

DOI: 10.2337/diaclin.26.3.100